antisense oligonucleotides

Posted on Sunday, July 1, 2012 - 09:41, By: Other
Bryan Traynor Even as some scientists work to develop animal and human cellular models of C9ORF72-related ALS (see C9ORF72 Research Models), others already are targeting the gene with experimental therapies designed to inactivate it or the repeat expansion it harbors.

Early results show ISIS-SOD1-Rx, an antisense drug directed against the SOD1 form of familial ALS, appears safe in the lowest-dose group

Posted on Wednesday, April 27, 2011 - 16:12, By: Margaret Wahl
  Update (July 21, 2014): This study was completed in 2012. ========================================================================== original story: