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Enrollment is open for a phase 2 trial of a drug normally used to treat abnormal heart rhythms that showed promise in ALS mouse studies
Posted on Monday, July 15, 2013 - 05:00, By: Amy Madsen
Update (June 16, 2014): This trial is now closed to new participants.
Update (Jan. 28, 2014): This story has been updated with new contact information for the Boston and St. Louis centers.
An interactive graphic provides details about six drugs currently being tested in the fight against ALS
Posted on Wednesday, May 1, 2013 - 09:30, By: Amy Madsen
Research seeking therapies for ALS is advancing at a rapid pace, and there are more potential treatments in clinical trials than ever before. Here, we look at six drugs currently in clinical trials for ALS: arimoclomol, Gilenya, ozanezumab, pyrimethamine, rasagiline and tirasemtiv.
How to use the...
Posted on Wednesday, May 1, 2013 - 09:23, By: Amy Madsen
How it works: Arimoclomol, developed by CytRx Corporation, is believed to work by increasing production of the so-called "chaperone" molecules heat-shock protein 70 and heat-shock protein 90. These molecules aid in cell repair by helping newly synthesized proteins fold correctly,...
South San Francisco biotech Cytokinetics has opened a 400-person clinical trial to evaluate the safety, tolerability and efficacy of tirasemtiv (formerly CK-2017357) in people with ALS
Posted on Thursday, September 20, 2012 - 05:00, By: Amy Madsen
Update (Dec. 30, 2013): According to a Dec. 3, 2013, press release from Cytokinetics, this trial is closed to new participants. More than 700 patients have enrolled, and results are expected in the first half of 2014.
Posted on Tuesday, March 1, 2011 - 11:15, By: Margaret Wahl
New insights and perspectives on the biology of ALS, best practices in the care of individuals with the disease and future directions for development of ALS therapies were the central themes of the 21st International Symposium on ALS/MND (Motor Neuron Disease) that took place in Orlando, Fla., Dec...
Posted on Tuesday, April 1, 2008 - 17:00, By: Margaret Wahl
Deciding whether to take an experimental medication outside or inside a clinical trial can be tough for people with ALS.