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Decreased activity of the 'transporter' protein MCT1 appears to result in insufficient energy support and eventual death of motor neurons in ALS research models
Posted on Monday, July 16, 2012 - 06:00, By: Other
Disruption of a “transporter” protein called MCT1 (also SL16A1) leads to the degeneration of muscle-controlling nerve cells (motor neurons) in animal and cell culture models of amyotrophic lateral sclerosis (ALS), an MDA-supported team of researchers has reported.
In addition, the team found that...
Posted on Sunday, July 1, 2012 - 09:39, By: Other
Phillip Wong, professor in the departments of pathology and neuroscience at Johns Hopkins University School of Medicine in Baltimore, is working — with MDA support — to develop research mouse models of C9ORF72-related ALS.
With colleagues, he plans to use the models to study more closely the...