exome sequencing

Twenty-five new genetic mutations were found in people with sporadic ALS but not in their parents, supporting the role of genetic contribution in the noninherited form of the disease

Posted on Friday, May 31, 2013 - 12:00, By: Amy Madsen
A team of researchers in the U.S. and Australia has shed new light on sporadic amyotrophic lateral sclerosis (ALS), finding that some people with the disorder have gene mutations that may be associated with ALS and that do not exist in either of their parents — so-called de novo mutations.