10 short items about the state of ALS science, including stem cells; trials and research models; risk factors; SOD1, TDP43 and C9ORF72 ALS-causing mutations; and more

Posted on Thursday, August 15, 2013 - 04:00, By: Amy Madsen
This roundup of recent amyotrophic lateral sclerosis (ALS) research and clinical trials news includes:

An apparent link between cognitive impairment and disease progression could have implications for identifying disease subtypes and better trial designs

Posted on Thursday, April 11, 2013 - 16:08, By: Amy Madsen
The presence of cognitive impairment within the first year after a diagnosis of amyotrophic lateral sclerosis (ALS) may be associated with more rapid decline in muscle function, a team of researchers in Ireland has reported. Conversely, the absence of cognitive impairment within the first year...

Research news items on the role of the p62 gene in ALS-FTD and the ALS-FTD-Q, a new screening tool for assessing behavioral disturbances in ALS

Posted on Wednesday, September 26, 2012 - 02:05, By: Amy Madsen
The most visible symptom in amyotrophic lateral sclerosis (ALS) is progressive weakness and loss of muscle control due to the loss of nerve cells called motor neurons. But approximately half of all people with ALS also exhibit some symptoms of cognitive impairment and associated behavioral symptoms...
Posted on Tuesday, November 1, 2011 - 10:00, By: Amy Madsen
John Shearer and his wife Brenda learned in November 2010 that he has ALS. The couple, who lives in Woodstock, Ga., were told the disease would cause gradual weakening of John’s voluntary muscles, such as those used for moving and breathing. John, 70, retired four months later in March 2011 from...
Posted on Tuesday, November 1, 2011 - 10:00, By: Amy Madsen
Editor's note: This is part of a larger story about the science and effects of frontotemporal dementia (FTD) in ALS. For more information, see When the Thinking Parts of the Brain Go Awry in ALS.

Cognitive changes, stem cells and an ALS immunization were discussed at the MDA Clinic Directors' Conference

Posted on Wednesday, March 4, 2009 - 14:37, By: ALSN Staff
Nearly 600 conferees gathered in Las Vegas Jan. 25-28 for the 2009 MDA National Clinic Directors Conference, where a number of experts presented a broad range of topics covering neuromuscular disease. One particular area of focus was ALS (amyotrophic lateral sclerosis, or Lou Gehrig's disease)....