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A gene variant is associated with ALS in French trial participants; focusing in on FUS; too much or too little TDP43 causes problems in fruit flies
Posted on Friday, June 14, 2013 - 05:00, By: Amy Madsen
Recent research in amyotrophic lateral sclerosis (ALS) includes findings involving the CRMP4, FUS and TDP43 genes.
Rare variant in the CRMP4 gene is associated with ALS
A study conducted in France and Sweden has identified an association between a rare variant in the gene for the collapsing...
Twenty-five new genetic mutations were found in people with sporadic ALS but not in their parents, supporting the role of genetic contribution in the noninherited form of the disease
Posted on Friday, May 31, 2013 - 12:00, By: Amy Madsen
A team of researchers in the U.S. and Australia has shed new light on sporadic amyotrophic lateral sclerosis (ALS), finding that some people with the disorder have gene mutations that may be associated with ALS and that do not exist in either of their parents — so-called de novo mutations.
Like a character from Dr. Seuss, the FUS ('foos') protein causes serious mischief when it strays from its normal location
Posted on Friday, July 1, 2011 - 13:53, By: Amy Madsen
In 2009, it was discovered that genetic mutations in the fused in sarcoma gene — FUS for short — were linked to some cases of ALS (amyotrophic lateral sclerosis, or Lou Gehrig’s disease).
A roundup of research about how the FUS gene and FUS protein may contribute to the development of amyotrophic lateral sclerosis
Posted on Thursday, May 12, 2011 - 16:37, By: Amy Madsen
The gene for FUS was associated in 2009 with some forms of ALS (amyotrophic lateral sclerosis, or Lou Gehrig’s disease).
Now, overlapping findings from four recent studies have revealed tantalizing clues about the molecular underpinnings of FUS-related forms of the disease.
Investigators have identified many more cases of ALS due to mutations in the gene for FUS in a variety of ethnic groups.
Posted on Friday, August 13, 2010 - 15:11, By: Margaret Wahl
Mutations in the gene for a protein called FUS may be a more widely distributed cause of amyotrophic lateral sclerosis (ALS) than previously recognized, according to three separate reports, all published in July 2010 in the journal Neurology.
Athena Diagnostics can now analyze five genes for mutations that cause familial ALS
Posted on Saturday, October 10, 2009 - 17:09, By: ALSN Staff
A new test panel that can detect “up to 35 percent” of the genetic flaws that can cause familial (inherited) ALS has been announced by Athena Diagnostics of Worcester, Mass.
Athena is a commercial laboratory specializing in DNA testing for neurological disorders.
Posted on Friday, February 27, 2009 - 09:01, By:
Two independent research teams, one based in the United States and Canada and the other in the United Kingdom and Australia, have identified mutations in a gene called FUS on chromosome 16 as a cause of familial amyotrophic lateral sclerosis (ALS).
Both groups announced their findings in the Feb....