profilin 1

Mutations in the profilin 1 gene are the cause of familial ALS in 1 to 2 percent of people with the disease

Posted on Friday, July 27, 2012 - 11:19, By: Amy Madsen
A genetic mutation in the gene for a protein called profilin 1 (PFN1) has been identified as a cause of familial amyotrophic lateral sclerosis (ALS), an MDA-supported team of researchers has reported. Only about 5 percent of ALS is familial (where there is a history of ALS in more than one family...