Five short items about the state of ALS science addressing: a therapy targeting SOD1; roles for TDP43 in behavior and body fat; respiratory care; and more

Posted on Tuesday, September 24, 2013 - 14:45, By: Amy Madsen
This roundup of recent amyotrophic lateral sclerosis (ALS) research and clinical trials news includes:

Two studies shed light on axonal transport, a critical process for nerve cell survival that appears to malfunction in amyotrophic lateral sclerosis (ALS)

Posted on Wednesday, July 3, 2013 - 05:00, By: Amy Madsen
Axonal transport is the process that is responsible for moving nutrients, proteins and other vital cellular cargo to and from the cell bodies in motor neurons — the muscle-controlling nerve cells that are lost in amyotrophic lateral sclerosis (ALS).
Posted on Monday, February 4, 2013 - 09:00, By: Amy Madsen
Everyone is born, and everyone dies. What happens in between — colds and flu, cardiac problems, cancer, amyotrophic lateral sclerosis (ALS) — is anyone's guess. And people do guess. It's common — indeed, almost universal — after receiving a diagnosis for any condition to question whether...

Updates on ALS research were presented at an international ALS conference in December 2012, including reports on SOD1, C9ORF72 and ALS risk factors

Posted on Wednesday, December 19, 2012 - 04:09, By: Amy Madsen
The 23rd International Symposium on ALS/MND (motor neuron disease), held in Chicago Dec. 5-7, 2012, brought together more than 900 researchers, clinicians and other health care professionals from 30 countries to hear presentations on the latest in ALS care and research.
Posted on Monday, October 1, 2012 - 09:45, By: Amy Madsen
Note: The research news featured in the October-December Research Roundup is a compilation of these MDA ALS News Online articles:

Decreased activity of the 'transporter' protein MCT1 appears to result in insufficient energy support and eventual death of motor neurons in ALS research models

Posted on Monday, July 16, 2012 - 06:00, By: Other
Disruption of a “transporter” protein called MCT1 (also SL16A1) leads to the degeneration of muscle-controlling nerve cells (motor neurons) in animal and cell culture models of amyotrophic lateral sclerosis (ALS), an MDA-supported team of researchers has reported. In addition, the team found that...

Astrocytes carrying mutated SOD1 genes transplanted into the spinal cords of healthy rats caused deterioration and death of nearby motor neurons

Posted on Friday, October 21, 2011 - 05:00, By: Amy Madsen
An MDA-supported team of scientists has demonstrated in rats that nervous system support cells called astrocytes carrying an SOD1 mutation cause neighboring motor neurons to deteriorate and die. The finding adds to a growing body of evidence that the star-shaped cells play a key role in the motor...