Five short items about the state of ALS science addressing: a therapy targeting SOD1; roles for TDP43 in behavior and body fat; respiratory care; and more

Posted on Tuesday, September 24, 2013 - 14:45, By: Amy Madsen
This roundup of recent amyotrophic lateral sclerosis (ALS) research and clinical trials news includes:

Five short items about the state of ALS science: addressing the way neurodegenerative disease spreads in the body; technology to detect free radicals; the immune system; and more

Posted on Thursday, September 5, 2013 - 05:00, By: Amy Madsen
This roundup of recent MDA-supported amyotrophic lateral sclerosis (ALS) research news and reviews includes:

Two studies yield different information about the role astrocytes — cells that normally protect motor neurons — play in the ALS disease process

Posted on Friday, March 29, 2013 - 11:43, By: Amy Madsen
Scientists continue to work at uncovering the biological mechanisms underlying amyotrophic lateral sclerosis (ALS). One area of intense study involves the potential role of central nervous system support cells called astrocytes. 
Posted on Monday, February 4, 2013 - 09:00, By: Amy Madsen
Everyone is born, and everyone dies. What happens in between — colds and flu, cardiac problems, cancer, amyotrophic lateral sclerosis (ALS) — is anyone's guess. And people do guess. It's common — indeed, almost universal — after receiving a diagnosis for any condition to question whether...

Three new MDA grants totaling nearly $1 million are helping scientists define the various processes that drive ALS

Posted on Monday, August 20, 2012 - 05:55, By: Amy Madsen
Three new MDA grants totaling $891,156 have been awarded to research projects aimed at uncovering some of the many complex processes that underlie ALS.

Mutations in the profilin 1 gene are the cause of familial ALS in 1 to 2 percent of people with the disease

Posted on Friday, July 27, 2012 - 11:19, By: Amy Madsen
A genetic mutation in the gene for a protein called profilin 1 (PFN1) has been identified as a cause of familial amyotrophic lateral sclerosis (ALS), an MDA-supported team of researchers has reported. Only about 5 percent of ALS is familial (where there is a history of ALS in more than one family...

Research about FUS-TDP43 interaction, a newly identified SOD1 mutation, and historical controls in trials; and webinars about the TDP43 mouse and the ceftriaxone trial

Posted on Friday, September 9, 2011 - 14:27, By: Amy Madsen
FUS and TDP43 work together in fruit flies In a fruit fly research model of inherited ALS, human FUS and TDP43 proteins work together on some processes necessary for the long-term survival of muscle-controlling nerve cells (motor neurons), reports a research team at Columbia University Medical...