TDP43 gene

Interactions between the ALS-associated FUS protein and the SMN protein, which is associated with SMA, indicate that the two motor neuron diseases are related

Posted on Thursday, October 4, 2012 - 04:05, By: Amy Madsen
New evidence links the motor neuron diseases ALS (amyotrophic lateral sclerosis) and spinal muscular atrophy (SMA), an international team of scientists has reported. The researchers say the findings could lead to the identification of therapeutic targets common to both disorders.

Decreased activity of the EPHA4 receptor leads to extended life span in animal models of ALS and SMA, and in people with ALS

Posted on Monday, September 3, 2012 - 05:00, By: Amy Madsen
Decreased activity of the EPHA4 receptor, which is encoded by the EPHA4 gene, increases life span in people with amyotrophic lateral sclerosis (ALS), a team of scientists has reported. The receptor, which was found to modify disease in zebrafish, mice, rats and humans, works together with a gene...

MDA’s innovative B2I research training program addresses the growing need for highly qualified translational researchers with expertise in modern drug research and development

Posted on Wednesday, August 1, 2012 - 06:00, By: Amy Madsen
MDA launched its innovative Bridge-to-Industry (B2I) program with a $180,000 grant over three years to postdoctoral fellow Archi Joardar at The University of Arizona in Tucson, to develop two promising drug candidates for the treatment of amyotrophic lateral sclerosis (ALS).