Cover Story

What we've learned about C90RF72 in ALS

Posted on Sunday, July 1, 2012 - 09:37, By: Other
In September 2011, two research teams working independently added chromosome 9 open reading frame 72 (C9ORF72) to the list of genes that, when mutated, can cause amyotrophic lateral sclerosis (ALS). The finding sparked a great deal of interest in the ALS research community for several reasons,...

MDA Art Collection celebrates 20th year

Posted on Monday, April 9, 2012 - 09:42, By: Richard Senti
Commemorating its 20th year of exhibiting the works of artists with neuromuscular disease, the Muscular Dystrophy Association Art Collection continues to demonstrate that physical disability is no barrier to creativity.

For Pat Dwyer, this newly approved respiratory assist device means 'a life better lived,' but physicians urge caution until more is known

Posted on Tuesday, January 3, 2012 - 09:49, By: Amy Madsen
Pat Dwyer of Kenmore, Wash., uses three different devices to make sure he’s getting enough air. A “sip-and-puff” ventilator supplements his breathing efforts during the day; bilevel positive airway pressure (BiPAP) helps him breathe at night; and the NeuRx Diaphragm Pacing System, or DPS,...
Posted on Tuesday, November 1, 2011 - 10:00, By: Amy Madsen
John Shearer and his wife Brenda learned in November 2010 that he has ALS. The couple, who lives in Woodstock, Ga., were told the disease would cause gradual weakening of John’s voluntary muscles, such as those used for moving and breathing. John, 70, retired four months later in March 2011 from...
Posted on Thursday, September 1, 2011 - 10:50, By: Amy Madsen
In its latest round of funding this July, MDA awarded nine grants totaling more than $2.5 million to research projects focused on uncovering the causes of, and developing therapies for, amyotrophic lateral sclerosis (ALS). The new grants were awarded to investigators at labs in the United States...
Posted on Friday, July 1, 2011 - 14:29, By: Miriam Davidson
Karen Felzer studies earthquakes, not ALS. But after her father learned he had the disease, Felzer helped conduct a study that caused a small shake-up in the world of ALS research. Working with Humberto Macedo, a Brazilian computer analyst who also had ALS, Felzer initiated an online, patient- and...

Five different but important strategies are under investigation by MDA-supported ALS researchers

Posted on Sunday, May 1, 2011 - 13:35, By: Amy Madsen
ALS is a disease that holds tight to its many secrets, even after decades of relentless pressure by dedicated and well-qualified researchers. Part of the complexity of ALS is that it involves multiple biological components and pathways, presents in many forms, and likely is caused, in whole or in...