MDA/ALS Newsmagazine Vol. 17, No. 3

July-September 2012

Cover Story

What we've learned about C90RF72 in ALS
In September 2011, two research teams working independently added chromosome 9 open reading frame 72 (C9ORF72) to the list of genes that, when mutated, can cause amyotrophic lateral sclerosis (ALS). The finding sparked a great deal of interest in the ALS research community for several reasons,...

Features

An urgent need exists for biomarkers — biological indicators — in ALS research that can be used: for diagnostic purposes; to measure disease progression; and to reliably assess the effects of experimental drugs in clinical trials. “If you compare a disease like ALS to multiple sclerosis [MS], you’...
I’ve always loved to travel and I planned to continue to travel even after being diagnosed with ALS in 1999 (thankfully, a slow-progressing form). I especially wanted to visit Israel, drawn by the history, the culture and the chance to reconnect to my Jewish roots. Could I do it in a wheelchair? Is...
Phillip Wong, professor in the departments of pathology and neuroscience at Johns Hopkins University School of Medicine in Baltimore, is working — with MDA support — to develop research mouse models of C9ORF72-related ALS. With colleagues, he plans to use the models to study more closely the me...

Research Roundup

Note: The research news featured in the July-September Research Roundup is a compilation of these MDA ALS News Online articles: Patient Assistance Program Launched for Nuedexta, June 8 MDA Symposium Puts Glial Cells in the Spotlight, May 31 Neuralstem Seeks to Expand Stem Cell Trial, May 16...

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