ALSN News (online only)
A gene variant is associated with ALS in French trial participants; focusing in on FUS; too much or too little TDP43 causes problems in fruit flies
Posted on Friday, June 14, 2013 - 05:00, By: Amy Madsen
Recent research in amyotrophic lateral sclerosis (ALS) includes findings involving the CRMP4, FUS and TDP43 genes.
Rare variant in the CRMP4 gene is associated with ALS
A study conducted in France and Sweden has identified an association between a rare variant in the gene for the collapsing response mediator protein 4 (CRMP4) protein and ALS.
A gene variant appears to modify ALS disease course in men; benefits seen from growth factors delivered by stem cells; antioxidant genes reduce cellular stress
Posted on Thursday, June 6, 2013 - 11:43, By: Amy Madsen
Identification of the biological mechanisms that underlie amyotrophic lateral sclerosis (ALS) may provide scientists with important clues about the disease that may be used to identify biomarkers and potential biological targets for t
Twenty-five new genetic mutations were found in people with sporadic ALS but not in their parents, supporting the role of genetic contribution in the noninherited form of the disease
Posted on Friday, May 31, 2013 - 12:00, By: Amy Madsen
A team of researchers in the U.S. and Australia has shed new light on sporadic amyotrophic lateral sclerosis (ALS), finding that some people with the disorder have gene mutations that may be associated with ALS and that do not exist in either of their parents — so-called de novo mutations.
Neuralstem reports that participants with limb-onset ALS who were early in their disease course had better outcomes in its trial
Posted on Wednesday, May 22, 2013 - 01:27, By: Amy Madsen
Recently announced data from a phase 1 clinical trial of NSI-566 neural stem cells in people with amyotrophic lateral sclerosis (ALS) show that a subset of trial participants had better outcomes than the others.
Newest clinic to be designated an MDA/ALS center is located at Louisiana State University (LSU) Health Sciences Center New Orleans School of Medicine
Posted on Tuesday, May 21, 2013 - 05:00, By: Amy Madsen
The Muscular Dystrophy Association has designated the MDA clinic at Louisiana State University Health Sciences Center School of Medicine in New Orleans as an MDA/ALS center. This brings the total number of these specialized clinics to 44.
Genervon Biopharmaceuticals has launched a phase 2 trial to test its experimental drug GM604 in people with amyotrophic lateral sclerosis
Posted on Thursday, May 16, 2013 - 17:29, By: Amy Madsen
A phase 2 clinical trial to test the experimental drug GM604 in people with amyotrophic lateral sclerosis (ALS) has opened at two trial sites in the United States. Enrollment is expected to begin soon.
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