Indications of Safety, Efficacy in BrainStorm Stem Cell Trial

Indications of Safety, Efficacy in BrainStorm Stem Cell Trial

NurOwn stem cell technology, currently being tested in Israel, appears safe and seems to improve breathing, swallowing and muscle strength

ALS Biomarkers Study Seeks 250 Participants

ALS Biomarkers Study Seeks 250 Participants

Researchers are seeking participants for a study to identify accurate biological indicators of ALS onset, progression and response to treatment

Immunomodulator CTLA4-FC Being Tested in ALS Mouse Model

Immunomodulator CTLA4-FC Being Tested in ALS Mouse Model

With funding from MDA, the ALS Therapy Development Institute is testing whether the immune system modulator CTLA4-FC slows disease progression in ALS mice

ALS TDI Teams with Two Biotechs to Develop Therapy

ALS TDI Teams with Two Biotechs to Develop Therapy

The MDA-supported ALS Therapy Development Institute will collaborate with Biogen Idec and UCB to test CDP7657, a compound that modulates the immune system

Phase 2 Trial of ALS Drug Yields Encouraging Results

Phase 2 Trial of ALS Drug Yields Encouraging Results

Trial participants receiving the highest dose of CK-2017357 showed symptom improvement in the first stage of an ongoing phase 2 trial of this experimental drug

Cover Story
Pat Dwyer of Kenmore, Wash., uses three different devices to make sure he’s getting enough air. A “sip-and-puff” ventilator supplements his breathing efforts during the day; bilevel positive airway pr...
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Dexpramipexole shows efficacy in ALS Newly published data confirm that in a two-part phase 2 clinical trial, the experimental therapy dexpramipexole showed dose-related slowing of symptom progression...
One of the first things that comes with a diagnosis of ALS is the determination of which “form” a person has: familial or sporadic. Sometimes it appears obvious. If there’s a known history of the...
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