Immunomodulator CTLA4-FC Being Tested in ALS Mouse Model
With funding from MDA, the ALS Therapy Development Institute is testing whether the immune system modulator CTLA4-FC slows disease progression in ALS mice
ALS TDI Teams with Two Biotechs to Develop Therapy
The MDA-supported ALS Therapy Development Institute will collaborate with Biogen Idec and UCB to test CDP7657, a compound that modulates the immune system
Phase 2 Trial of ALS Drug Yields Encouraging Results
Trial participants receiving the highest dose of CK-2017357 showed symptom improvement in the first stage of an ongoing phase 2 trial of this experimental drug
Pat Dwyer of Kenmore, Wash., uses three different devices to make sure he’s getting enough air. A “sip-and-puff” ventilator supplements his breathing efforts during the day; bilevel positive airway pr...
Dexpramipexole shows efficacy in ALS
Newly published data confirm that in a two-part phase 2 clinical trial, the experimental therapy dexpramipexole showed dose-related slowing of symptom progression...
One of the first things that comes with a diagnosis of ALS is the determination of which “form” a person has: familial or sporadic.
Sometimes it appears obvious. If there’s a known history of the...
Fight smart, not just hard. That’s the motto of Richard Bedlack, a world-renowned ALS research warrior who directs the ALS Clinic at Duke University, Durham, N.C. “Everyone I’ve ever met who is...