ALSN News (online only)

Several research groups have published new findings about how various gene flaws cause ALS and how their effects might be counteracted

Posted on Wednesday, April 1, 2015 - 13:34, By: Margaret Wahl
Understanding the many roads that can lead to amyotrophic lateral sclerosis (ALS) is a painstaking but necessary prerequisite to development of disease-modifying treatments. Recently, several research teams have made contributions to this effort. A 2011 MDA career development grant to Adrian Israelson, who was then at the University of California, San Diego, was crucial to the finding that the...

A phase 2 trial of neural stem cell transplantation was mostly well tolerated, with about half the patients responding to the treatment

Posted on Tuesday, March 17, 2015 - 11:23, By: Margaret Wahl
Maryland-based biotechnology company Neuralstem announced in a March 12, 2014, press release, that a phase 2 trial of its NSI-566 neural stem cells in 15 people with amyotrophic lateral sclerosis (ALS) has shown that the surgical transplantation procedure and the cells themselves, up to a dose of 16

Investigational drug GM604 has shown some intriguing results in a very small number of ALS patients

Posted on Thursday, January 22, 2015 - 10:13, By: Margaret Wahl
Biopharmaceutical company Genervon has announced what it considers encouraging  results from a "compassionate use" trial of its experimental drug GM604 in a single patient with advanced amyotrophic lateral sclerosis (ALS).

 

Posted on Tuesday, January 13, 2015 - 12:04, By: Margaret Wahl
Update (March 17, 2015): Neuralstem announced on March 12, 2015, that a phase 2 trial to test transplantation into the spinal cord of its NSI-566 neural stem cells showed the procedure was generally safe and well tolerated in 15 ALS patients (with one exception) and that stabilization or improvement in grip strength or overall motor function was seen in seven of the 15.

Stanford University is collecting samples of blood, muscle and other tissues from people with neuromuscular disorders for use in research

Posted on Wednesday, January 7, 2015 - 15:36, By: Margaret Wahl
Ever wondered how someone with a neuromuscular disorder in his or her family might contribute to research efforts in this field?

MDA has joined forces with the ALS Association to fight ALS through a grant to James Shorter at the University of Pennsylvania

Posted on Wednesday, December 3, 2014 - 14:09, By: Margaret Wahl
MDA has joined forces with the ALS Association (ALSA) to fund a new research project aimed at finding a potential therapy for amyotrophic lateral sclerosis (ALS). The two organizations have made a $240,000 award to molecular biologist James Shorter at the Perelman School of Medicine at the University of Pennsylvania. Shorter also has an existing MDA grant for related research.

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